Treatment and Dosing

Zuprevo (tildipirosin) Antibiotic
Treats BRD

Effective and Economical

The daily treatment cost of Zuprevo is less than the cost of a cup of coffee a day.

Calculate Daily Costs

Zuprevo (tildipirosin) antibiotic is a powerful new macrolide that exhibits extended duration in the lungs for the treatment of bovine respiratory disease (BRD) and respiratory disease in cattle at high-risk of developing BRD. Zuprevo concentrates at the site of the action – in the lungs – for 28 days1 and in bronchial fluid for 21 days1 to treat BRD caused by Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. Plus, Zuprevo reaches peak plasma concentration in just 45 minutes.

Additional Zuprevo Features:

  • One low-volume dose for more doses per bottle
  • Easy-to-calibrate 1 mL/100 lbs dose
  • Easy-to-use formulation – highly syringeable


Antibiotic Dose Volume per 100 LBS Dose Volume per 500 LBS
Zuprevo (tildipirosin) 1 mL 5 mL
Draxxin® (tulathromycin) 1.14 mL 5.5 mL
Zactran® (gamithromycin) 1.83 mL 9.1 mL
Micotil® (tilmicosin injection) 1.5 mL 7.5 mL


No matter what the weather, Zuprevo (tildipirosin) antibiotic is highly syringeable for easy administration.

Meat Withdrawal

Zuprevo features a 21-day withdrawal time. This timeframe gives producers the flexibility to make quick decisions based on current market conditions.

1Menge, M. et al., Pharmacokinetics of tildipirosin in bovine plasma, lung tissue, and bronchial fluid (from live, non-anesthetized cattle). J Vet Pharm Therap. Doj: 10.1111/J. 1365-2885, 2011. 1349.x. The correlation between pharmacokinetic data and clinical relevance is unknown.

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